Bone-Targeting AAV-Mediated Gene Silencing in Osteoclasts for Osteoporosis Therapy

Improper activity of bone-resorbing osteoclasts results in low bone density and deterioration of bone structure, which increase the risk of fractures. Anti-resorptive therapies targeting osteoclasts have proven effective in preserving bone mass, but these therapeutic agents lead to defective new bon...

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Detalles Bibliográficos
Autores principales: Yang, Yeon-Suk, Xie, Jun, Chaugule, Sachin, Wang, Dan, Kim, Jung-Min, Kim, JiHea, Tai, Phillip W.L., Seo, Seok-kyo, Gravallese, Ellen, Gao, Guangping, Shim, Jae-Hyuck
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210389/
https://www.ncbi.nlm.nih.gov/pubmed/32405514
http://dx.doi.org/10.1016/j.omtm.2020.04.010

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210389/
https://www.ncbi.nlm.nih.gov/pubmed/32405514
http://dx.doi.org/10.1016/j.omtm.2020.04.010

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