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SIRT2 Contributes to the Regulation of Intestinal Cell Proliferation and Differentiation

BACKGROUND AND AIMS: Intestinal mucosa undergoes a continual process of proliferation, differentiation, and apoptosis. Disruption of this homeostasis is associated with disorders such as inflammatory bowel disease (IBD). We investigated the role of Sirtuin 2 (SIRT2), a NAD-dependent protein deacetyl...

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Detalles Bibliográficos
Autores principales: Li, Chang, Zhou, Yuning, Rychahou, Piotr, Weiss, Heidi L., Lee, Eun Y., Perry, Courtney L., Barrett, Terrence A., Wang, Qingding, Evers, B. Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210478/
https://www.ncbi.nlm.nih.gov/pubmed/31954883
http://dx.doi.org/10.1016/j.jcmgh.2020.01.004