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Shear Stress Triggers Angiogenesis of Late Endothelial Progenitor Cells via the PTEN/Akt/GTPCH/BH4 Pathway

BACKGROUND: Shear stress is an effective modulator of endothelial progenitor cells (EPCs) and has been suggested to play an important role in angiogenesis. The phosphatase and tensin homolog (PTEN)/Akt and guanosine triphosphate cyclohydrolase (GTPCH)/tetrahydrobiopterin (BH4) pathways regulate the...

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Detalles Bibliográficos
Autores principales: Wu, Shao-Hong, Zhang, Feng, Yao, Shun, Tang, Lu, Zeng, Hai-Tao, Zhu, Ling-Ping, Yang, Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210539/
https://www.ncbi.nlm.nih.gov/pubmed/32399044
http://dx.doi.org/10.1155/2020/5939530