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Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer

Hepatocellular carcinoma (HCC) represents 80% of the primary hepatic neoplasms. It is the sixth most frequent neoplasm, the fourth cause of cancer-related death, and 7% of registered malignancies. Sorafenib is the first line molecular targeted therapy for patients in advanced stage of HCC. The prese...

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Detalles Bibliográficos
Autores principales: González, Raúl, Rodríguez-Hernández, María A., Negrete, María, Ranguelova, Kalina, Rossin, Aurelie, Choya-Foces, Carmen, Cruz-Ojeda, Patricia de la, Miranda-Vizuete, Antonio, Martínez-Ruiz, Antonio, Rius-Pérez, Sergio, Sastre, Juan, Bárcena, José A., Hueber, Anne-Odile, Padilla, C. Alicia, Muntané, Jordi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210585/
https://www.ncbi.nlm.nih.gov/pubmed/32388267
http://dx.doi.org/10.1016/j.redox.2020.101528