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Isocitrate dehydrogenase 2 deficiency aggravates prolonged high-fat diet intake-induced hypertension
The development of hypertension is associated with mitochondrial redox balance disruptions. NADP(+)-dependent isocitrate dehydrogenase 2 (IDH2) plays an important role in the maintenance of mitochondrial redox balance by producing mitochondrial NADPH, which is an essential cofactor in the reduction...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210593/ https://www.ncbi.nlm.nih.gov/pubmed/32388270 http://dx.doi.org/10.1016/j.redox.2020.101548 |