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N6-methyladenosine methyltransferase METTL3 affects the phenotype of cerebral arteriovenous malformation via modulating Notch signaling pathway

BACKGROUND: Cerebral arteriovenous malformation (AVM) is a serious life-threatening congenital cerebrovascular disease. Specific anatomical features, such as nidus size, location, and venous drainage, have been validated to affect treatment outcomes. Until recently, molecular biomarkers and correspo...

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Detalles Bibliográficos
Autores principales: Wang, Lin-jian, Xue, Yimeng, Huo, Ran, Yan, Zihan, Xu, Hongyuan, Li, Hao, Wang, Jia, Zhang, Qian, Cao, Yong, Zhao, Ji-zong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210675/
https://www.ncbi.nlm.nih.gov/pubmed/32384926
http://dx.doi.org/10.1186/s12929-020-00655-w