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CRISPR screening identifies M1AP as a new MYC regulator with a promoter-reporter system

BACKGROUND: MYC is one of the proto-oncogenes contributing to tumorigenesis in many human cancers. Although the mechanism of MYC regulation is still not fully understood, learning about the comprehensive mechanism controlling the transcriptional activity of MYC will lead to therapeutic targets. The...

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Detalles Bibliográficos
Autores principales: Yamamoto, Akiko, Kurata, Morito, Onishi, Iichiroh, Sugita, Keisuke, Matsumura, Miwa, Ishibashi, Sachiko, Ikeda, Masumi, Yamamoto, Kouhei, Kitagawa, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210806/
https://www.ncbi.nlm.nih.gov/pubmed/32411526
http://dx.doi.org/10.7717/peerj.9046