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CRISPR screening identifies M1AP as a new MYC regulator with a promoter-reporter system
BACKGROUND: MYC is one of the proto-oncogenes contributing to tumorigenesis in many human cancers. Although the mechanism of MYC regulation is still not fully understood, learning about the comprehensive mechanism controlling the transcriptional activity of MYC will lead to therapeutic targets. The...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
PeerJ Inc.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210806/ https://www.ncbi.nlm.nih.gov/pubmed/32411526 http://dx.doi.org/10.7717/peerj.9046 |