Relevance of Caspase-1 and Nlrp3 Inflammasome on Inflammatory Bone Resorption in A Murine Model of Periodontitis

This study investigates the role of NLRP3 inflammasome and its main effector Caspase-1 in inflammation and alveolar bone resorption associated with periodontitis. Heat-killed Aggregatibacter actinomycetemcomitans (Aa) was injected 3x/week (4 weeks) into gingival tissues of wild-type (WT), Nlrp3-KO a...

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Detalles Bibliográficos
Autores principales: Rocha, Fernanda R G., Delitto, Andrea E., de Souza, Joao A. Chaves, González-Maldonado, Laura A., Wallet, Shannon M., Rossa Junior, Carlos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210885/
https://www.ncbi.nlm.nih.gov/pubmed/32385413
http://dx.doi.org/10.1038/s41598-020-64685-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210885/
https://www.ncbi.nlm.nih.gov/pubmed/32385413
http://dx.doi.org/10.1038/s41598-020-64685-y

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