The pivot point arginines identified in the β-pinwheel structure of C-terminal domain from Salmonella Typhi DNA Gyrase A subunit

The essentiality of DNA Gyrase in basic cellular processes in bacterial pathogens makes it an ideal drug target. Though the Gyrase has a conserved mechanism of action, the complete DNA wrapping and binding process is still unknown. In this study, we have identified six arginine residues R556, R612,...

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Detalles Bibliográficos
Autores principales: Sachdeva, Ekta, Kaur, Gurpreet, Tiwari, Pragya, Gupta, Deepali, Singh, Tej P., Ethayathulla, Abdul S., Kaur, Punit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210945/
https://www.ncbi.nlm.nih.gov/pubmed/32385379
http://dx.doi.org/10.1038/s41598-020-64792-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210945/
https://www.ncbi.nlm.nih.gov/pubmed/32385379
http://dx.doi.org/10.1038/s41598-020-64792-w

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