Dysregulation of the EphrinB2−EphB4 ratio in pediatric cerebral arteriovenous malformations is associated with endothelial cell dysfunction in vitro and functions as a novel noninvasive biomarker in patients

We investigated (1) EphrinB2 and EphB4 receptor expression in cerebral AVMs, (2) the impact of an altered EphrinB2:EphB4 ratio on brain endothelial cell function and (3) potential translational applications of these data. The following parameters were compared between AVM endothelial cells (AVMECs)...

Descripción completa

Detalles Bibliográficos
Autores principales: Fehnel, Katie Pricola, Penn, David L., Duggins-Warf, Micah, Gruber, Maxwell, Pineda, Steven, Sesen, Julie, Moses-Gardner, Alexander, Shah, Nishali, Driscoll, Jessica, Zurakowski, David, Orbach, Darren B., Smith, Edward R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210966/
https://www.ncbi.nlm.nih.gov/pubmed/32286515
http://dx.doi.org/10.1038/s12276-020-0414-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210966/
https://www.ncbi.nlm.nih.gov/pubmed/32286515
http://dx.doi.org/10.1038/s12276-020-0414-0

Ejemplares similares