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Dysregulation of the EphrinB2−EphB4 ratio in pediatric cerebral arteriovenous malformations is associated with endothelial cell dysfunction in vitro and functions as a novel noninvasive biomarker in patients

We investigated (1) EphrinB2 and EphB4 receptor expression in cerebral AVMs, (2) the impact of an altered EphrinB2:EphB4 ratio on brain endothelial cell function and (3) potential translational applications of these data. The following parameters were compared between AVM endothelial cells (AVMECs)...

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Detalles Bibliográficos
Autores principales:	Fehnel, Katie Pricola, Penn, David L., Duggins-Warf, Micah, Gruber, Maxwell, Pineda, Steven, Sesen, Julie, Moses-Gardner, Alexander, Shah, Nishali, Driscoll, Jessica, Zurakowski, David, Orbach, Darren B., Smith, Edward R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210966/ https://www.ncbi.nlm.nih.gov/pubmed/32286515 http://dx.doi.org/10.1038/s12276-020-0414-0

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