Mechanoradicals in tensed tendon collagen as a source of oxidative stress

As established nearly a century ago, mechanoradicals originate from homolytic bond scission in polymers. The existence, nature and biological relevance of mechanoradicals in proteins, instead, are unknown. We here show that mechanical stress on collagen produces radicals and subsequently reactive ox...

Descripción completa

Detalles Bibliográficos
Autores principales: Zapp, Christopher, Obarska-Kosinska, Agnieszka, Rennekamp, Benedikt, Kurth, Markus, Hudson, David M., Mercadante, Davide, Barayeu, Uladzimir, Dick, Tobias P., Denysenkov, Vasyl, Prisner, Thomas, Bennati, Marina, Daday, Csaba, Kappl, Reinhard, Gräter, Frauke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210969/
https://www.ncbi.nlm.nih.gov/pubmed/32385229
http://dx.doi.org/10.1038/s41467-020-15567-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210969/
https://www.ncbi.nlm.nih.gov/pubmed/32385229
http://dx.doi.org/10.1038/s41467-020-15567-4

Ejemplares similares