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Longitudinal optical imaging technique to visualize progressive axonal damage after brain injury in mice reveals responses to different minocycline treatments

A high-resolution, three-dimensional, optical imaging technique for the murine brain was developed to identify the effects of different therapeutic windows for preclinical brain research. This technique tracks the same cells over several weeks. We conducted a pilot study of a promising drug to treat...

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Detalles Bibliográficos
Autores principales: Pernici, Chelsea D., Rowe, Rachel K., Doughty, P. Timothy, Madadi, Mahboubeh, Lifshitz, Jonathan, Murray, Teresa A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7210987/
https://www.ncbi.nlm.nih.gov/pubmed/32385407
http://dx.doi.org/10.1038/s41598-020-64783-x