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Human microbiota-transplanted C57BL/6 mice and offspring display reduced establishment of key bacteria and reduced immune stimulation compared to mouse microbiota-transplantation

Transplantation of germ-free (GF) mice with microbiota from mice or humans stimulates the intestinal immune system in disparate ways. We transplanted a human microbiota into GF C57BL/6 mice and a murine C57BL/6 microbiota into GF C57BL/6 mice and Swiss-Webster (SW) mice. Mice were bred to produce an...

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Detalles Bibliográficos
Autores principales: Lundberg, Randi, Toft, Martin F., Metzdorff, Stine B., Hansen, Camilla H. F., Licht, Tine R., Bahl, Martin I., Hansen, Axel K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211022/
https://www.ncbi.nlm.nih.gov/pubmed/32385373
http://dx.doi.org/10.1038/s41598-020-64703-z