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HotSpotAnnotations—a database for hotspot mutations and annotations in cancer
Hotspots, recurrently mutated DNA positions in cancer, are thought to be oncogenic drivers because random chance is unlikely and the knowledge of clear examples of oncogenic hotspots in genes like BRAF, IDH1, KRAS and NRAS among many other genes. Hotspots are attractive because provide opportunities...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Oxford University Press
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211031/ https://www.ncbi.nlm.nih.gov/pubmed/32386297 http://dx.doi.org/10.1093/database/baaa025 |