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HotSpotAnnotations—a database for hotspot mutations and annotations in cancer

Hotspots, recurrently mutated DNA positions in cancer, are thought to be oncogenic drivers because random chance is unlikely and the knowledge of clear examples of oncogenic hotspots in genes like BRAF, IDH1, KRAS and NRAS among many other genes. Hotspots are attractive because provide opportunities...

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Detalles Bibliográficos
Autor principal: Trevino, Victor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211031/
https://www.ncbi.nlm.nih.gov/pubmed/32386297
http://dx.doi.org/10.1093/database/baaa025