Cargando…
Thrombospondin‐1 mediates Drp‐1 signaling following ischemia reperfusion in the aging heart
BACKGROUND: Ischemia reperfusion (IR) injury leads to activation of dynamin‐related protein (Drp‐1), causing mitochondrial fission and generation of reactive oxygen species (ROS), but the molecular mechanisms that activate Drp‐1 are not known. The purpose of this study was to establish a link betwee...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
John Wiley and Sons Inc.
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211039/ https://www.ncbi.nlm.nih.gov/pubmed/32395703 http://dx.doi.org/10.1096/fba.2019-00090 |