A new SIRT1 inhibitor, MHY2245, induces autophagy and inhibits energy metabolism via PKM2/mTOR pathway in human ovarian cancer cells

Ovarian cancer is a common gynecological cancer that is found worldwide. Class III histone deacetylase (HDAC) inhibitors, a new class of anticancer agents, induce autophagy in various human cancer cells. The aim of the present study was to investigate the antitumor activity of MHY2245, a new synthet...

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Detalles Bibliográficos
Autores principales: Tae, In Hwan, Son, Ji Yeon, Lee, Su Hyun, Ahn, Mi-Young, Yoon, Kyungsil, Yoon, Sungpil, Moon, Hyung Ryong, Kim, Hyung Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211172/
https://www.ncbi.nlm.nih.gov/pubmed/32398958
http://dx.doi.org/10.7150/ijbs.44343

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211172/
https://www.ncbi.nlm.nih.gov/pubmed/32398958
http://dx.doi.org/10.7150/ijbs.44343

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