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Enhancement of The Stability of Human Growth Hormone by Using Tris(hydroxymethyl)aminomethane: Molecular Docking and Experimental Analysis

OBJECTIVE: It is so difficult to formulate human growth hormone (hGH) in a solution with high stability and new drug delivery system (NDDs) due to physiochemical instability. The purpose of this study was to investigate the possibility of using Tris as a hGH stabilizer. MATERIALS AND METHODS: In thi...

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Detalles Bibliográficos
Autores principales: Mirzaei, Siyavash, Mobedi, Hamid, Gourabi, Hamid, Sanati, Mohammad Hosein, Khezli, Sakine, Omidian, Hamid, Ighaeie, Masoume
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211290/
https://www.ncbi.nlm.nih.gov/pubmed/32347033
http://dx.doi.org/10.22074/cellj.2021.6903