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The Effect of Arbutin on The Expression of Tumor Suppressor P53, BAX/BCL-2 Ratio and Oxidative Stress Induced by Tert-Butyl Hydroperoxide in Fibroblast and LNcap Cell Lines

OBJECTIVE: Arbutin (p-hydroxyphenyl-β-D-glucopyranoside) possesses beneficial functions including antioxidant, anti- inflammatory, and anti-tumoral activities. Due to the important role of oxidative stress and apoptosis in the successful treatment of cancer, understanding mechanisms that lead to apo...

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Detalles Bibliográficos
Autores principales: Ebadollahi, Shima, Pouramir, Mahdi, Zabihi, Ebrahim, Golpour, Monireh, Aghajanpour-Mir, Mohse
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royan Institute 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211292/
https://www.ncbi.nlm.nih.gov/pubmed/32347047
http://dx.doi.org/10.22074/cellj.2021.6902