Pharmacokinetic Evaluation by Modeling and Simulation Analysis of a Donepezil Patch Formulation in Healthy Male Volunteers

INTRODUCTION: This study characterized the pharmacokinetics (PKs) of a donepezil patch formulation currently under development, using mixed effect modeling analysis, and explored optimal patch dosing regimens in comparison with the donepezil oral formulation. METHODS: PK data used in this analysis w...

Descripción completa

Detalles Bibliográficos
Autores principales: Yoon, Seok Kyu, Bae, Kyun-Seop, Hong, Dong Hyun, Kim, Seong Su, Choi, Young Kweon, Lim, Hyeong-Seok
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211298/
https://www.ncbi.nlm.nih.gov/pubmed/32440098
http://dx.doi.org/10.2147/DDDT.S244957

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211298/
https://www.ncbi.nlm.nih.gov/pubmed/32440098
http://dx.doi.org/10.2147/DDDT.S244957

Ejemplares similares