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Pharmacokinetic Evaluation by Modeling and Simulation Analysis of a Donepezil Patch Formulation in Healthy Male Volunteers

INTRODUCTION: This study characterized the pharmacokinetics (PKs) of a donepezil patch formulation currently under development, using mixed effect modeling analysis, and explored optimal patch dosing regimens in comparison with the donepezil oral formulation. METHODS: PK data used in this analysis w...

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Detalles Bibliográficos
Autores principales:	Yoon, Seok Kyu, Bae, Kyun-Seop, Hong, Dong Hyun, Kim, Seong Su, Choi, Young Kweon, Lim, Hyeong-Seok
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2020
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211298/ https://www.ncbi.nlm.nih.gov/pubmed/32440098 http://dx.doi.org/10.2147/DDDT.S244957

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