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Intrinsically disordered regions are abundant in simplexvirus proteomes and display signatures of positive selection

Whereas the majority of herpesviruses co-speciated with their mammalian hosts, human herpes simplex virus 2 (HSV-2, genus Simplexvirus) most likely originated from the cross-species transmission of chimpanzee herpesvirus 1 to an ancestor of modern humans. We exploited the peculiar evolutionary histo...

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Detalles Bibliográficos
Autores principales: Mozzi, Alessandra, Forni, Diego, Cagliani, Rachele, Clerici, Mario, Pozzoli, Uberto, Sironi, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211401/
https://www.ncbi.nlm.nih.gov/pubmed/32411391
http://dx.doi.org/10.1093/ve/veaa028