Tetrandrine alleviates cerebral ischemia/reperfusion injury by suppressing NLRP3 inflammasome activation via Sirt-1

BACKGROUND & AIMS: Tetrandrine (Tet) has been reported to have anti-inflammatory effects and protect from the ischemic strokes. The NLRP3 inflammasome plays a key role in cerebral ischemia/reperfusion (I/R)-induced inflammatory lesions. However, the molecular mechanisms of Tet related to the pro...

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Detalles Bibliográficos
Autores principales: Wang, Jun, Guo, Ming, Ma, Ruojia, Wu, Maolin, Zhang, Yamei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2020
Materias:
Cognitive Disorders
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211409/
https://www.ncbi.nlm.nih.gov/pubmed/32419986
http://dx.doi.org/10.7717/peerj.9042

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211409/
https://www.ncbi.nlm.nih.gov/pubmed/32419986
http://dx.doi.org/10.7717/peerj.9042

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