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Triple combination of interferon beta-1b, lopinavir–ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial

BACKGROUND: Effective antiviral therapy is important for tackling the coronavirus disease 2019 (COVID-19) pandemic. We assessed the efficacy and safety of combined interferon beta-1b, lopinavir–ritonavir, and ribavirin for treating patients with COVID-19. METHODS: This was a multicentre, prospective...

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Detalles Bibliográficos
Autores principales: Hung, Ivan Fan-Ngai, Lung, Kwok-Cheung, Tso, Eugene Yuk-Keung, Liu, Raymond, Chung, Tom Wai-Hin, Chu, Man-Yee, Ng, Yuk-Yung, Lo, Jenny, Chan, Jacky, Tam, Anthony Raymond, Shum, Hoi-Ping, Chan, Veronica, Wu, Alan Ka-Lun, Sin, Kit-Man, Leung, Wai-Shing, Law, Wai-Lam, Lung, David Christopher, Sin, Simon, Yeung, Pauline, Yip, Cyril Chik-Yan, Zhang, Ricky Ruiqi, Fung, Agnes Yim-Fong, Yan, Erica Yuen-Wing, Leung, Kit-Hang, Ip, Jonathan Daniel, Chu, Allen Wing-Ho, Chan, Wan-Mui, Ng, Anthony Chin-Ki, Lee, Rodney, Fung, Kitty, Yeung, Alwin, Wu, Tak-Chiu, Chan, Johnny Wai-Man, Yan, Wing-Wah, Chan, Wai-Ming, Chan, Jasper Fuk-Woo, Lie, Albert Kwok-Wai, Tsang, Owen Tak-Yin, Cheng, Vincent Chi-Chung, Que, Tak-Lun, Lau, Chak-Sing, Chan, Kwok-Hung, To, Kelvin Kai-Wang, Yuen, Kwok-Yung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211500/
https://www.ncbi.nlm.nih.gov/pubmed/32401715
http://dx.doi.org/10.1016/S0140-6736(20)31042-4