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Cancer cell lines show high heritability for motility but not generation time

Tumour evolution depends on heritable differences between cells in traits affecting cell survival or replication. It is well established that cancer cells are genetically and phenotypically heterogeneous; however, the extent to which this phenotypic variation is heritable is far less well explored....

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Detalles Bibliográficos
Autores principales: Wass, Anastasia V., Butler, George, Taylor, Tiffany B., Dash, Philip R., Johnson, Louise J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211847/
https://www.ncbi.nlm.nih.gov/pubmed/32431868
http://dx.doi.org/10.1098/rsos.191645