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A game-theoretic approach to deciphering the dynamics of amyloid-β aggregation along competing pathways

Aggregation of amyloid-β (Aβ) peptides is a significant event that underpins Alzheimer's disease (AD). Aβ aggregates, especially the low-molecular weight oligomers, are the primary toxic agents in AD pathogenesis. Therefore, there is increasing interest in understanding their formation and beha...

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Detalles Bibliográficos
Autores principales: Ghosh, Preetam, Rana, Pratip, Rangachari, Vijayaraghavan, Saha, Jhinuk, Steen, Edward, Vaidya, Ashwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211858/
https://www.ncbi.nlm.nih.gov/pubmed/32431878
http://dx.doi.org/10.1098/rsos.191814