Pancreatic cancer triggers diabetes through TGF-β–mediated selective depletion of islet β-cells

Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease that remains incurable because of late diagnosis, which renders any therapeutic intervention challenging. Most PDAC patients develop de novo diabetes, which exacerbates their morbidity and mortality. How PDAC triggers diabetes is still unfo...

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Detalles Bibliográficos
Autores principales: Parajuli, Parash, Nguyen, Thien Ly, Prunier, Céline, Razzaque, Mohammed S, Xu, Keli, Atfi, Azeddine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Life Science Alliance LLC 2020
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211975/
https://www.ncbi.nlm.nih.gov/pubmed/32371554
http://dx.doi.org/10.26508/lsa.201900573

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211975/
https://www.ncbi.nlm.nih.gov/pubmed/32371554
http://dx.doi.org/10.26508/lsa.201900573

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