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Reversal of hyperactive subthalamic circuits differentially mitigates pain hypersensitivity phenotypes in parkinsonian mice
Although pain is a prevalent nonmotor symptom in Parkinson’s disease (PD), it is undertreated, in part because of our limited understanding of the underlying mechanisms. Considering that the basal ganglia are implicated in pain sensation, and that their synaptic outputs are controlled by the subthal...
Autores principales: | Luan, Yiwen, Tang, Dongliang, Wu, Haichuan, Gu, Weixin, Wu, Yuqing, Cao, Jun-Li, Xiao, Cheng, Zhou, Chunyi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7211985/ https://www.ncbi.nlm.nih.gov/pubmed/32312820 http://dx.doi.org/10.1073/pnas.1916263117 |
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