LSM2-8 and XRN-2 contribute to the silencing of H3K27me3-marked genes through targeted RNA decay

In fission yeast and plants, RNA-processing and degradation contribute to heterochromatin silencing, alongside conserved pathways of transcriptional repression. It was unknown if similar pathways exist in metazoans. Here we describe a pathway of silencing in C. elegans somatic cells, in which the hi...

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Detalles Bibliográficos
Autores principales: Mattout, Anna, Gaidatzis, Dimos, Padeken, Jan, Schmid, Christoph, Aeschlimann, Florian, Kalck, Véronique, Gasser, Susan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212045/
https://www.ncbi.nlm.nih.gov/pubmed/32251399
http://dx.doi.org/10.1038/s41556-020-0504-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212045/
https://www.ncbi.nlm.nih.gov/pubmed/32251399
http://dx.doi.org/10.1038/s41556-020-0504-1

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