In Vivo Suppression of Autophagy via Lentiviral shRNA Targeting Atg5 Improves Lupus-Like Syndrome

In both mouse models and clinical patients with lupus, autophagy levels were significantly elevated and correlated with disease activity. Furthermore, autophagy can promote the survival of B and T cells, plasma cell differentiation, and antibody production. These results suggest that autophagy may p...

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Detalles Bibliográficos
Autores principales: Liu, Chi-Jui, Tang, Shye-Jye, Chou, Chun-Che, Sun, Guang-Huan, Sun, Kuang-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212279/
https://www.ncbi.nlm.nih.gov/pubmed/32462028
http://dx.doi.org/10.1155/2020/8959726

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212279/
https://www.ncbi.nlm.nih.gov/pubmed/32462028
http://dx.doi.org/10.1155/2020/8959726

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