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The Effects of Age and Cell Isolation on Collagen II Synthesis by Articular Chondrocytes: Evidence for Transcriptional and Posttranscriptional Regulation

Adult articular cartilage synthesises very little type II collagen in comparison to young cartilage. The age-related difference in collagen II synthesis is poorly understood. This is the first systematic investigation of age-related differences in extracellular matrix synthesis in fresh articular ca...

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Detalles Bibliográficos
Autores principales: Asopa, Vipin, Vincent, Tonia, Saklatvala, Jeremy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212282/
https://www.ncbi.nlm.nih.gov/pubmed/32461985
http://dx.doi.org/10.1155/2020/4060135