MASP-2 Is a Heparin-Binding Protease; Identification of Blocking Oligosaccharides

It is well-known that heparin and other glycosaminoglycans (GAGs) inhibit complement activation. It is however not known whether fractionation and/or modification of GAGs might deliver pathway-specific inhibition of the complement system. Therefore, we evaluated a library of GAGs and their derivativ...

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Detalles Bibliográficos
Autores principales: Talsma, Ditmer T., Poppelaars, Felix, Dam, Wendy, Meter-Arkema, Anita H., Vivès, Romain R., Gál, Peter, Boons, Geert-Jan, Chopra, Pradeep, Naggi, Annamaria, Seelen, Marc A., Berger, Stephan P., Daha, Mohamed R., Stegeman, Coen A., van den Born, Jacob
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212410/
https://www.ncbi.nlm.nih.gov/pubmed/32425936
http://dx.doi.org/10.3389/fimmu.2020.00732

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212410/
https://www.ncbi.nlm.nih.gov/pubmed/32425936
http://dx.doi.org/10.3389/fimmu.2020.00732

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