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An Integrative Network Modeling Approach to T CD4 Cell Activation

The adaptive immune response is initiated by the interaction of the T cell antigen receptor/CD3 complex (TCR) with a cognate peptide bound to a MHC molecule. This interaction, along with the activity of co-stimulatory molecules and cytokines in the microenvironment, enables cells to proliferate and...

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Detalles Bibliográficos
Autores principales: Martínez-Méndez, David, Villarreal, Carlos, Mendoza, Luis, Huerta, Leonor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212416/
https://www.ncbi.nlm.nih.gov/pubmed/32425809
http://dx.doi.org/10.3389/fphys.2020.00380