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An Integrative Network Modeling Approach to T CD4 Cell Activation
The adaptive immune response is initiated by the interaction of the T cell antigen receptor/CD3 complex (TCR) with a cognate peptide bound to a MHC molecule. This interaction, along with the activity of co-stimulatory molecules and cytokines in the microenvironment, enables cells to proliferate and...
Autores principales: | Martínez-Méndez, David, Villarreal, Carlos, Mendoza, Luis, Huerta, Leonor |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212416/ https://www.ncbi.nlm.nih.gov/pubmed/32425809 http://dx.doi.org/10.3389/fphys.2020.00380 |
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