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WDHD1 Leads to Cisplatin Resistance by Promoting MAPRE2 Ubiquitination in Lung Adenocarcinoma

Ubiquitin ligases have been shown to regulate drug sensitivity. This study aimed to explore the role of the ubiquitin ligase WD repeat and HMG-box DNA binding protein 1 (WDHD1) in regulating cisplatin sensitivity in lung adenocarcinoma (LUAD). A quantitative analysis of the global proteome identifie...

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Detalles Bibliográficos
Autores principales: Gong, Lian, Xiao, Mengqing, He, Dong, Hu, Yi, Zhu, Yuxing, Xiang, Liang, Bao, Ying, Liu, Xiaoming, Zeng, Qinghai, Liu, Jianye, Zhou, Ming, Zhou, Yanhong, Cheng, Yaxin, Zhang, Yeyu, Deng, Liping, Zhu, Rongrong, Lan, Hua, Cao, Ke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212426/
https://www.ncbi.nlm.nih.gov/pubmed/32426268
http://dx.doi.org/10.3389/fonc.2020.00461