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Downregulation of eEF1A/EFT3-4 Enhances Dopaminergic Neurodegeneration After 6-OHDA Exposure in C. elegans Model

Parkinson’s disease (PD) is a neurodegenerative disorder characterized by the aggregation of α-synuclein protein and selective death of dopaminergic (DA) neurons in the substantia nigra of the midbrain. Although the molecular pathogenesis of PD is not completely understood, a recent study has report...

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Detalles Bibliográficos
Autores principales: Chalorak, Pawanrat, Dharmasaroja, Permphan, Meemon, Krai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212436/
https://www.ncbi.nlm.nih.gov/pubmed/32425742
http://dx.doi.org/10.3389/fnins.2020.00303