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Exact Distribution of Linkage Disequilibrium in the Presence of Mutation, Selection, or Minor Allele Frequency Filtering
Linkage disequilibrium (LD), often expressed in terms of the squared correlation (r(2)) between allelic values at two loci, is an important concept in many branches of genetics and genomics. Genetic drift and recombination have opposite effects on LD, and thus r(2) will keep changing until the effec...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212447/ https://www.ncbi.nlm.nih.gov/pubmed/32425975 http://dx.doi.org/10.3389/fgene.2020.00362 |