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BCG-induced trained immunity: can it offer protection against COVID-19?

Bacillus Calmette–Guérin (BCG) vaccination has been reported to decrease susceptibility to respiratory tract infections, an effect proposed to be mediated by the general long-term boosting of innate immune mechanisms, also termed trained immunity. Here, we discuss the non-specific beneficial effects...

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Bibliographic Details
Main Authors: O’Neill, Luke A. J., Netea, Mihai G.
Format: Online Article Text
Language:English
Published: Nature Publishing Group UK 2020
Subjects:
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212510/
https://www.ncbi.nlm.nih.gov/pubmed/32393823
http://dx.doi.org/10.1038/s41577-020-0337-y