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Inhibition of germinal vesicle breakdown using IBMX increases microRNA-21 in the porcine oocyte

BACKGROUND: Germinal vesicle breakdown (GVBD) occurs during oocyte meiotic maturation, a period when transcriptional processes are virtually inactive. Thus, the maturing oocyte is reliant on processes such as post-transcriptional gene regulation (PTGR) to regulate the mRNA and protein repertoire. Mi...

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Detalles Bibliográficos
Autores principales: Hale, Benjamin J., Li, Yunsheng, Adur, Malavika K., Ross, Jason W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212575/
https://www.ncbi.nlm.nih.gov/pubmed/32393269
http://dx.doi.org/10.1186/s12958-020-00603-1