The emerging roles of vacuolar-type ATPase-dependent Lysosomal acidification in neurodegenerative diseases

BACKGROUND: Lysosomes digest extracellular material from the endocytic pathway and intracellular material from the autophagic pathway. This process is performed by the resident hydrolytic enzymes activated by the highly acidic pH within the lysosomal lumen. Lysosome pH gradients are mainly maintaine...

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Detalles Bibliográficos
Autores principales: Song, Qiaoyun, Meng, Bo, Xu, Haidong, Mao, Zixu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212675/
https://www.ncbi.nlm.nih.gov/pubmed/32393395
http://dx.doi.org/10.1186/s40035-020-00196-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212675/
https://www.ncbi.nlm.nih.gov/pubmed/32393395
http://dx.doi.org/10.1186/s40035-020-00196-0

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