Conditional Single Vector CRISPR/SaCas9 Viruses for Efficient Mutagenesis in the Adult Mouse Nervous System

Mice engineered for conditional, cell type-specific gene inactivation have dominated the field of mouse genetics because of the high efficiency of Cre-loxP-mediated recombination. Recent advances in CRISPR/Cas9 technologies have provided alternatives for rapid gene mutagenesis for loss-of-function (...

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Detalles Bibliográficos
Autores principales: Hunker, Avery C., Soden, Marta E., Krayushkina, Dasha, Heymann, Gabriel, Awatramani, Rajeshwar, Zweifel, Larry S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212805/
https://www.ncbi.nlm.nih.gov/pubmed/32209486
http://dx.doi.org/10.1016/j.celrep.2020.02.092

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212805/
https://www.ncbi.nlm.nih.gov/pubmed/32209486
http://dx.doi.org/10.1016/j.celrep.2020.02.092

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