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Conditional Single Vector CRISPR/SaCas9 Viruses for Efficient Mutagenesis in the Adult Mouse Nervous System

Mice engineered for conditional, cell type-specific gene inactivation have dominated the field of mouse genetics because of the high efficiency of Cre-loxP-mediated recombination. Recent advances in CRISPR/Cas9 technologies have provided alternatives for rapid gene mutagenesis for loss-of-function (...

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Detalles Bibliográficos
Autores principales:	Hunker, Avery C., Soden, Marta E., Krayushkina, Dasha, Heymann, Gabriel, Awatramani, Rajeshwar, Zweifel, Larry S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212805/ https://www.ncbi.nlm.nih.gov/pubmed/32209486 http://dx.doi.org/10.1016/j.celrep.2020.02.092

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