Gut Microbiome-Modified Polyphenolic Compounds Inhibit α-Synuclein Seeding and Spreading in α-Synucleinopathies

Misfolding, aggregation and deposition of α-synuclein (α-syn) are major pathologic characteristics of Parkinson’s disease (PD) and the related synucleinopathy, multiple system atrophy (MSA). The spread of α-syn pathology across brain regions is thought to play a key role in the onset and progression...

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Detalles Bibliográficos
Autores principales: Yamasaki, Tritia R., Ono, Kenjiro, Ho, Lap, Pasinetti, Giulio M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212829/
https://www.ncbi.nlm.nih.gov/pubmed/32431588
http://dx.doi.org/10.3389/fnins.2020.00398

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212829/
https://www.ncbi.nlm.nih.gov/pubmed/32431588
http://dx.doi.org/10.3389/fnins.2020.00398

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