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The CREB-binding protein inhibitor ICG-001: a promising therapeutic strategy in sporadic meningioma with NF2 mutations

BACKGROUND: Meningiomas with Neurofibromin 2 gene mutations (NF2-mutant meningiomas) account for ~40% of the sporadic meningiomas. However, there is still no effective drug treatment for the disease. METHODS: Expression profile of Merlin protein was explored through immunohistochemistry in a meningi...

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Detalles Bibliográficos
Autores principales: Deng, Jiaojiao, Hua, Lingyang, Han, Tao, Tian, Mi, Wang, Daijun, Tang, Hailiang, Sun, Shuchen, Chen, Hong, Cheng, Haixia, Zhang, Tao, Xie, Qing, Wan, Lixin, Zhu, Hongda, Gong, Ye
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212891/
https://www.ncbi.nlm.nih.gov/pubmed/32642722
http://dx.doi.org/10.1093/noajnl/vdz055