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Structures Illuminate Cardiac Ion Channel Functions in Health and in Long QT Syndrome

The cardiac action potential is critical to the production of a synchronized heartbeat. This electrical impulse is governed by the intricate activity of cardiac ion channels, among them the cardiac voltage-gated potassium (K(v)) channels KCNQ1 and hERG as well as the voltage-gated sodium (Na(v)) cha...

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Detalles Bibliográficos
Autores principales: Brewer, Kathryn R., Kuenze, Georg, Vanoye, Carlos G., George, Alfred L., Meiler, Jens, Sanders, Charles R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7212895/
https://www.ncbi.nlm.nih.gov/pubmed/32431610
http://dx.doi.org/10.3389/fphar.2020.00550