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BSCI-03. T CELL EXHAUSTION SIGNATURES VARY BY TUMOR TYPE AND ARE INDEPENDENT OF INTRACRANIAL LOCATION

T-cell exhaustion is a hindrance to the efficacy of immune checkpoint blockade. This study is among the first to examine, and credential as bona fide, exhaustion among T cells infiltrating murine models of brain metastasis, including breast, lung, and melanoma cancers. Furthermore, this study demons...

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Detalles Bibliográficos
Autores principales: Woroniecka, Karolina, Chongsathidkiet, Pakawat, Cui, Xiuyu, Dechant, Cosette, Wilkinson, Daniel, Fecci, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213120/
http://dx.doi.org/10.1093/noajnl/vdz014.002