Cargando…

BSCI-04. TARGETING TRIPLE-NEGATIVE BREAST CANCER BRAIN METASTASES WITH A RE-ENGINEERED LUPUS AUTOANTIBODY

An unusual lupus anti-DNA autoantibody, 3E10, has potential to be used against triple-negative breast cancer (TNBC) brain metastases. 3E10 penetrates live cell nuclei, inhibits DNA repair, and is selectively toxic to cancer cells with the PTEN and/or DNA-damage response (DDR)-deficiencies that are a...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Shenqi, May, Christopher, Shirali, Anupama, Dubljevic, Valentina, Campbell, James, Zhou, Jiangbing, Hansen, James
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2019
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213175/ http://dx.doi.org/10.1093/noajnl/vdz014.003

Ejemplares similares

64. AN ENT2-DEPENDENT, CELL-PENETRATING, AND DNA-DAMAGING LUPUS AUTOANTIBODY CROSSES THE BLOOD-BRAIN BARRIER TO TARGET BRAIN TUMORS
por: Rattray, Zahra, et al.
Publicado: (2020)

ENT2 facilitates brain endothelial cell penetration and blood-brain barrier transport by a tumor-targeting anti-DNA autoantibody
por: Rattray, Zahra, et al.
Publicado: (2021)

BSCI-04 TARGETING THE PI3K-MTOR PATHWAY TO TREAT UBE2C-DRIVEN BRAIN METASTASES
por: Paisana, Eunice, et al.
Publicado: (2022)

BSCI
por: Shannon Michael J
Publicado: (2004)

BSCI-05 REPURPOSING PROPOFOL FOR THE TREATMENT OF BRAIN METASTASES
por: Penning, Donald, et al.
Publicado: (2022)

BSCI-06 COMPREHENSIVE ANALYSIS OF THE IMMUNOGENOMICS OF TRIPLE NEGATIVE BREAST CANCER BRAIN METASTASES FROM LCCC1419
por: Van Swearingen, Amanda, et al.
Publicado: (2022)

BSCI-20. THERAPEUTIC TARGETING OF HLA-G IN BRAIN METASTASES
por: Singh, Sheila, et al.
Publicado: (2019)

BSCI-04. Tumor-educated platelets promote breast cancer brain metastasis and therapeutic resistance
por: Tabet, Elie, et al.
Publicado: (2021)

A lupus anti-DNA autoantibody mediates autocatalytic, targeted delivery of nanoparticles to tumors
por: Chen, Zeming, et al.
Publicado: (2016)

BSCI-07. BONE MARROW T-CELL SEQUESTRATION IN THE SETTING OF BRAIN METASTASES
por: Chongsathidkiet, Pakawat, et al.
Publicado: (2019)

BSCI-21 COX4I1 EXPRESSION IN BRAIN METASTASES
por: Saad, Mahak, et al.
Publicado: (2022)

BSCI-13. MTH1 expression is upregulated in brain metastases of malignant melanoma
por: Timmer, Marco
Publicado: (2021)

BSCI-12. COMPREHENSIVE GENOMIC ANALYSIS OF BRAIN METASTASES FROM MULTIPLE CANCER TYPES
por: Fukumura, Kazutaka, et al.
Publicado: (2019)

BSCI-14. tGLI1 is an actionable therapeutic target in breast cancer brain metastases
por: Doheny, Daniel, et al.
Publicado: (2021)

CCNP BSCI quick reference sheets.
por: Stewart, Brent, et al.
Publicado: (2006)

CCNP BSCI portable command guide
por: Empson, Scott
Publicado: (2007)

CCNP BSCI official exam certification guide
por: Stewart, Brent, et al.
Publicado: (2007)

BSCI-02. tGLI1 IS A NOVEL, ACTIONABLE TARGET FOR THE TREATMENT OF BREAST CANCER BRAIN METASTASES
por: Doheny, Daniel, et al.
Publicado: (2019)

BSCI-23. TISSUE FACTOR SIGNALING ENHANCES METASTATIC BRAIN CANCER MALIGNANCY
por: Unruh, Dusten, et al.
Publicado: (2019)

BSCI-09. MECHANISMS OF ENHANCED DRUG DELIVERY IN BRAIN METASTASES WITH FOCUSED ULTRASOUND-INDUCED BLOOD-TUMOR BARRIER DISRUPTION
por: Ferraro, Gino, et al.
Publicado: (2019)

BSCI-10. Invasive growth of brain metastases is driven by cancer cell-pSTAT3+ reactive astrocyte crosstalk
por: Dankner, Matthew, et al.
Publicado: (2021)

BSCI-18 ESTROGEN-DEPLETION DECREASES PROGRESSION OF ER¯ BRAIN METASTASES BY PROMOTING AN ANTI-TUMORAL LOCAL IMMUNE RESPONSE
por: Contreras-Zarate, Maria, et al.
Publicado: (2022)

BSCI-09. Multiomic single cell analysis reveals emerging principles of tumor immune microenvironment inherent to NSCLC brain metastases
por: Wen, Lei, et al.
Publicado: (2021)

BSCI-07. Multiomics characterization of brain metastases in multiple histologies identifies enrichment of oxidative phosphorylation as a promising therapeutic target
por: Fukumura, Kazutaka, et al.
Publicado: (2021)

BSCI-02 CSF PROTEOMICS AS A MINIMALLY-INVASIVE STRATEGY FOR DISTINGUISHING BRAIN METASTASES FROM OTHER PRIMARY BRAIN MALIGNANCIES
por: Mansouri, Alireza, et al.
Publicado: (2022)

DNA-dependent targeting of cell nuclei by a lupus autoantibody
por: Weisbart, Richard H., et al.
Publicado: (2015)

A nucleolytic lupus autoantibody is toxic to BRCA2-deficient cancer cells
por: Noble, Philip W., et al.
Publicado: (2014)

Lots of autoantibodies equal lupus?
por: Aringer, Martin, et al.
Publicado: (2013)

Building scalable Cisco internetworks (BSCI): authorized self-study guide
por: Paquet, Catherine, et al.
Publicado: (2006)

BSCI-17. YOUNG AGE PROMOTES BREAST CANCER METASTASIS TO THE BRAIN
por: Wu, Alex, et al.
Publicado: (2019)

BSCI-19. Therapeutic intervention of lung-, breast-, and melanoma-brain metastasis
por: Kieliszek, Agata, et al.
Publicado: (2021)

BSCI-01. Small RNAseq analysis of microRNAs in brain metastasis
por: Jancalek, Radim, et al.
Publicado: (2021)

BSCI-07 ACETYL-AMANTADINE AS A DIAGNOSTIC BIOMARKER IN PATIENTS WITH GLIOBLASTOMA
por: Mann, Anmol, et al.
Publicado: (2022)

Targeted Delivery of Secretory Promelittin via Novel Poly(lactone‐co‐β‐amino ester) Nanoparticles for Treatment of Breast Cancer Brain Metastases
por: Zhou, Yu, et al.
Publicado: (2020)

BSCI-06. Phage display biopanning identifies Amot regulating cell motility in brain metastasis-initiating cells
por: She, Chunhua, et al.
Publicado: (2021)

BSCI-27. MELATONIN REDUCES MALIGNANCY OF BREAST CANCER BRAIN METASTATIC CELLS
por: Gil, Beatriz Fernandez, et al.
Publicado: (2019)

BSCI-10. NEUROLOGICAL DYSFUNCTION CAUSED BY BRAIN TUMOR-GENERATED SOLID STRESS IS REVERSED BY LITHIUM
por: Seano, Giorgio, et al.
Publicado: (2019)

Protective natural autoantibodies and lupus pathogenesis
por: Silverman, Gregg J
Publicado: (2014)

SURG-04. SIMULTANEOUS CRANIOTOMIES FOR MULTIPLE BRAIN METASTASES
por: Gassie, Kelly, et al.
Publicado: (2019)

BSCI-01 INTRATHECAL DELIVERY OF DENDRITIC CELL VACCINE ERADICATES TUMOR GROWTH AND PROTECTS AGAINST LEPTOMENINGEAL DISEASE (LMD) RE-INOCULATION IN IMMUNOCOMPETENT HER2+ AND TRIPLE NEGATIVE BREAST CANCER (TNBC) LMD XENOGRAFT MODELS
por: Law, Vincent, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_kbj4v4pslr0qcrjlgl5pak026v