Mitochondrial DNA Stress Signalling Protects the Nuclear Genome

The mammalian genome comprises nuclear DNA (nDNA) derived from both parents and mitochondrial DNA (mtDNA) that is maternally inherited and encodes essential proteins required for oxidative phosphorylation. Thousands of copies of the circular mtDNA are present in most cell types that are packaged by...

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Detalles Bibliográficos
Autores principales: Wu, Zheng, Oeck, Sebastian, West, A. Phillip, Mangalhara, Kailash C., Sainz, Alva G., Newman, Laura E., Zhang, Xiao-Ou, Wu, Lizhen, Yan, Qin, Bosenberg, Marcus, Liu, Yanfeng, Sulkowski, Parker L., Tripple, Victoria, Kaech, Susan M., Glazer, Peter M., Shadel, Gerald S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2019
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213273/
https://www.ncbi.nlm.nih.gov/pubmed/32395698
http://dx.doi.org/10.1038/s42255-019-0150-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213273/
https://www.ncbi.nlm.nih.gov/pubmed/32395698
http://dx.doi.org/10.1038/s42255-019-0150-8

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