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CBMS-05 COMPREHENSIVE METABOLOMIC ANALYSIS OF IDH1R132H CLINICAL GLIOMA SAMPLES REVEALS SUPPRESSION OF Β-OXIDATION DUE TO CARNITINE DEFICIENCY

BACKGROUND: Gliomas with isocitrate dehydrogenase 1 (IDH1) mutation have alterations in several enzyme activities, resulting in various metabolic changes. The aim of this study was to investigate the mechanism for the better prognosis of gliomas with IDH mutation by performing metabolomic analysis....

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Detalles Bibliográficos
Autores principales: Miyata, Satsuki, Tominaga, Kaoru, Sakashita, Eiji, Urabe, Masashi, Onuki, Yoshiyuki, Gomi, Akira, Yamaguchi, Takashi, Mieno, Makiko, Mizukami, Hiroaki, Kume, Akihiro, Ozawa, Keiya, Watanabe, Eijyu, Kawai, Kensuke, Endou, Hitoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7213357/
http://dx.doi.org/10.1093/noajnl/vdz039.025